Nephropathia epidemica in Finland

a clinical, histological and epidemiological study by Juhani Lähdevirta in Helsinki

Written in English
Published: Pages: 154 Downloads: 49
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SeriesAnnals of clinical research -- v. 3. Suppl. ; 8
The Physical Object
Pagination154 p.
Number of Pages154
ID Numbers
Open LibraryOL18020055M

nephropathy[nə′fräpəthē] (medicine) Any disease of the kidney. nephrosis Nephropathy a general term that includes several renal disorders. Classified as nephropathies are nephropathy of pregnancy and a group of other kidney diseases that are distinguished from each other by a variety of morphological changes. This latter group of diseases.   Abstract. Circulating immune complexes (CICs), immunoconglutinins, and antiglobulins were studied in nephropathia epidemica, an acute infectious hemorrhagic feCited by: Hantaviruses are enveloped RNA viruses each carried by a specific rodent species. Three hantaviruses, Puumala, Dobrava, and Saaremaa viruses, are known to cause haemorrhagic fever with renal syndrome. In Europe, Puumala causes a generally mild disease, nephropathia epidemica, which presents most commonly with fever, headache, gastrointestinal symptoms, Cited by: J. Clement, P. Maes, M. Barrios, W.W. Verstraeten, S. Amirpour Haredasht, Geneviève Ducoffre, J-M Aerts and M. Van Ranst (October 5th ). Global Warming and Epidemic Trends of an Emerging Viral Disease in Western-Europe: The Nephropathia Epidemica Case, Global Warming Impacts - Case Studies on the Economy, Human Health, and on Urban and Natural Cited by: 8.

nephropathy [nĕ-frop´ah-the] 1. any disease of the kidneys. adj., adj nephropath´ic. 2. any disease of the kidneys; see also nephritis. Called also nephrosis. adj., adj nephropath´ic. AIDS nephropathy former name for HIV-associated nephropathy. analgesic nephropathy interstitial nephritis with renal papillary necrosis, seen in patients with a Missing: Finland. The clinical disease known as nephropathia epidem-ica (NE) was first described in on the basis of cases seen in northern Sweden [1, 2]. Over the next several decades many additional isolated or small clusters of cases were reported from northern Sweden, Norway, and Finland [3]. The first major outbreaks were reported during World War II, when. Niklasson B, LeDuc JW. Epidemiology of nephropathia epidemica in Sweden. J Infect Dis ; Xu ZY, Guo CS, Wu YL, Zhang XW, Liu K. Epidemiological studies of hemorrhagic fever with renal syndrome. Analysis of risk factors and mode of transmission. J Infect Dis ; Prince HN, Prince DL, Prince RN. Nephropathia epidemica (NE) is a clinical entity with a close relationship to the hemorrhagic fever with renal syndrome. The disease has been described by Myhrman (2) and Zetterholm (2) in Sweden. In Finland the first and also largest outbreak occurred during World War II, when during three months over German and 60 Finnish soldiers in a.

nephropathia epidemica: a generally benign form of epidemic hemorrhagic fever reported in Scandinavia. The pathogenesis of PUUV nephropathia epidemica is complex and multifactorial, and the risk factors for severe acute kidney injury (AKI) during acute PUUV infection are not well defined. We conducted a prospective study of hospitalized patients with PUUV infection in Tampere, Finland to identify acute illness risk factors for HFRS by: James. W. LeDuc, James E. Childs, Greg E. Glass, and A. J. Watson *. Hemorrhagic fever with renal syndrome (HFRS) is a disease which has not gained widespread recognition among clinicians in the United States, but which is, in fact, of considerable significance in many parts of .

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Nephropathia epidemica was described as a " new " disease in Sweden inbut the first account in English appeared in [Bull. Hyg.,v. 26, ]. The illness has an acute febrile influenza-like onset, usually without catarrhal symptoms, but by about the fourth clay a second phase is Nephropathia epidemica in by:   Nephropathia epidemica (NE or epidemic nephropathy) is a mild type of HFRS in which haemorrhaging is rare.

“Approximately 10 per cent of NE patients show clinical symptoms of haemorrhaging. These symptoms are usually mild, such as nosebleed or obscured field of vision as haemorrhaging in the vascular system of the eye causes blurry vision,” says Tomas.

Clinical characteristics of nephropathia epidemica in Sweden: prospective study of 74 cases. Settergren B, Juto P, Trollfors B, Wadell G, Norrby SR Rev.

Infect. Usually PUUV causes mild HFRS (also called nephropathia epidemica [NE]). In Finland, 1,–3, NE cases are diagnosed annually, i.e., ≈60 cases/, persons during years when the vole population peaks.

Almost % of infected persons recover, and long-lasting complications are by: A spontaneous recovery followed all cases described. In Myhrman proposed nephropathia epidemica (NE) as the name for this disease.

During the subsequent decades, a large number of cases of this disease were reported from Scandinavia and Finland (Myhrman; Lahdevirta ).Cited by: PUUV is endemic in northern Europe (mostly in Sweden and Finland) and may cause a generally mild form of HFRS, which is also called “ Nephropathia epidemica.” Seoul virus (SEOV) is globally widespread and may cause moderate HFRS.

Nephropathia epidemica has occurred in Scandinavia, western Russia, and other parts of Europe. Mild hemorrhagic illness can also result from infection with the Other articles where Nephropathia epidemica is discussed: hantavirus: A second HFRS disease, nephropathia epidemica, is usually not g: Finland.

However, the mechanism of the hemorrhagic lesions needs further exploration. (Gastrointest Endosc ;) Nephropathia epidemica (NE) is the Scandinavian form of hemorrhagic fever with renal syndrome. NE was first described in in Swedish patients by Myhrman1,2 and Zetterholm.3 Later, Cited by: The incidence of Nephropathia Epidemica (NE) was determined for various regions of Sweden and compared with the NE antibody prevalence rates in normal population.

Book Review Book Review Gruskin, Alan Lee HW () Korean haemorrhagic fever. Prog Med Virol L/ihdevirta J () Nephropathia epidemica in Finland. A clinical, histological and epidemiological study. Am Clin Res 3 [Suppl 8]: Author: Gruskin, Alan.

Nephropathia epidemica virus, the etiological agent of hemorrhagic fever with renal syndrome in Scandinavia, was serially propagated in Mongolian gerbils (Meriones unguiculatus). Lähdevirta J. Nephropathia epidemica in Finland: a clinical histological and epidemiological study.

Ann Clin Res Suppl. ; Settergren B, Juto P, Wadell G. Detection of specific serum immunoglobulin M in nephropathia epidemica (Scandinavian epidemic nephropathy) by a biotin-avidin-amplified immunofluorescence method. J Cited by: 8. A mild form of HFRS, named nephropathia epidemica (NE) occurs widely in Finland, Scandinavia, western Russia and several other areas in Europe.

The causative agent, Puumala virus (PUUV), is a member of the genus Hantavirus in the Bunyaviridae family. Its natural host is the bank vole (Clethrionomys glareolus).

In Finland, approximately 1, Korpela H, Lähdevirta J. The role of small rodents and patterns of living in the epidemiology of nephropathia epidemica. Scand J Infect Dis. ; 10 (4)– Lähdevirta J. Nephropathia epidemica in Finland.

A clinical histological and epidemiological study. Ann Clin Res. ; – LeDuc JW, Smith GA, Johnson KM. Puumala virus (PUUV), by far the most frequent cause of hantavirus disease in Germany (7), causes a milder form of HFRS (8) called nephropathia epidemica (NE).

Hantavirus infections are one of the 5 most common notifiable viral diseases in Germany, along with norovirus infections, hepatitis C, influenza, and rotavirus infections (7).Cited by:   Brummer-Korvenkontio, M, et al.

() Epidemiological study of nephropathia epidemica in Finland Scandinavian Journal of Infectious Disea – / by: 1. Anti-endothelial cell antibodies in nephropathia epidemica and other viral diseases A.

WANGEL. TEMONEN*. BRUMMER-KORVENKONTIO* & A. VAHERI* Department of Bacteriology and Immunology, and * Department of Virology. University of Helsinki.

Helsinki. Finland f Accepted for publication 14 July ) SUMMARY. We report ophthalmological findings in 15 cases of nephropathia epidemica. The patients, 13 men and 2 women, were 20 to 62 (mean 30) years of age.

The onset of the disease was characterized by high fever, nausea, headache, abdominal pain, backache, somnolence, red throat, proteinuria, and oliguria. The symptoms subsided rapidly during the polyuria stage.

Puumala virus infection (nephropathia epidemica) as different diagnosis of acute renal failure History: A year old patient presented in reduced status with a sudden onset of fever, headache, backpain, abdominal pain, mild diarrhea, nausea with vomiting, and blurred by: 1.

The human infection is characterized by a mild-to-moderate form of hemorrhagic fever with renal syndrome designated nephropathia epidemica (NE), with a case fatality rate of.

We present the complete genome of PUUV directly recovered from a person with fatal infection. Usually PUUV causes mild HFRS (also called nephropathia epidemica [NE]). In Finland, 1,–3, NE cases are diagnosed annually, i.e., ≈60 cases/, persons during years when the vole population peaks (7).

Today we knew more than strains of this virus are antigenically related. Seroepidemiological studies have revealed worldwide occurrence of the infection (5). The severe form of HVD is more often seen in the Far East (6).

In Europe the mild form, known as nephropathia epidemica (NE),is found in Scandinavia (7) and Western Europe (8).Cited by: 8. Usually PUUV causes mild HFRS (also called nephropathia epidemica [NE]).

In Finland, 1, NE cases are diagnosed annually, i.e., [approximately equals] 60 cases/, persons during years when the vole population peaks (7). Almost % of infected persons recover, and long-lasting complications are rare.

Enter search terms. Keep search filters New search. Advanced search. viruses Article Evaluation of Real-Time RT-PCR for Diagnostic Use in Detection of Puumala Virus Silja Niskanen 1, Anne Jääskeläinen 1,2, Olli Vapalahti 1,2,3 and Tarja Sironen 1,3,* 1 Department of Virology, University of Helsinki, Helsinki, Finland 2 Department of Virology and Immunology, Helsinki University Hospital Laboratory (HUSLAB), Helsinki, FinlandCited by: 1.

Nephropathia epidemica (NE) is endemic in Scandinavia, European Russia, and the Balkans (Lee and van der Groen, ). Mustonen et al. () stated that the causative agent, Puumala virus, is a member of the hantavirus genus.

An indirect immunofluorescence test for detection of serum antibodies specific for nephropathia epidemica (NE) has been developed with use of acetone-fixed cryostat sections of the lungs of bank voles (Clethrionomys glareolus) that had been trapped from the NE-endemic area in Finland as antigen.

NE antigen was detected as distinct fluorescence in the cytoplasm Cited by: Puumala virus causes nephropathia epidemica, a rodent-borne zoonosis that is endemic to Europe.

We sequenced the complete Puumala virus genome that was directly recovered from a person who died and compared it with those of viruses from local bank voles. The virus strain involved was neither a unique nor rare genetic variant.

Intraocular pressure changes in nephropathia epidemica. A prospective study of 37 patients with acute systemic Puumala virus infection.

Ophthalmology ; (12): – Google Scholar | Crossref | Medline. Lahdevirta, J. Nephropathia epidemica in Finland. A clinical, Author: Alexandre Baillieul, Tich Ludovic Le, Jean-François Rouland. Human infection with Puumala virus (PUUV), the most common hantavirus in Central Europe, causes nephropathia epidemica (NE), a disease characterized by acute kidney injury and thrombocytopenia.

Hemostatic Impairment in Nephropathia Epidemica S 7. Brummer-Korvenkontio M, Henttonen H, Vaheri A. Hemor-rhagic fever with renal syndrome in Finland: ecology and virology of nephropathia epidemica. Scand J Infect Dis [Suppl] ; 8. Lahdevirta J. Clinical features of HFRS in Scandinavia as compared with East Asia.

Scand J Infect. Lähdevirta J. Nephropathia epidemica in Finland. A clinical histological and epidemiological study. Ann Clin Res.

;– Lähdevirta J, Collan Y, Jokinen EJ, Hiltunen R. Renal sequelae to nephropathia epidemica. Acta Pathol Microbiol Scand [A].

;– Rubini ME, Jablon S, Mc DM.medicine. The milder form of HFRS, nephropathia epidemica, common in Fennoscandia (Scandinavia and Finland), was first described by Swedish authors in ,3 However, the infecting agent remained unknown untilwhen the Korean researcher H W Lee discovered that the lung tissues of striped field mice (Apodemus agrarius).